| Gene Symbol | ATG2A |
| Full Name | Autophagy Related 2A |
| Aliases | ATG2APROTEIN |
| Chromosome | 11q13.2 |
| Protein Type | Peripheral Membrane Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </b></td><td>ER membrane, autophagosome</td></tr> |
| Molecular Weight | 206 kDa |
| UniProt ID | [Q9BSB5](https://www.uniprot.org/uniprot/Q9BSB5) |
| GeneCards | ATG2A |
| Human Protein Atlas | ATG2A |
| N-terminal region | Contains a putative membrane-binding domain that interacts with the ER |
| Central region | Features WD40 repeat-like beta-propeller structures |
| C-terminal region | Contains the conserved ATG2 domain essential for autophagosome formation |
| Autophagosome formation | Acts as a scaffold protein during the initial stages of autophagosome biogenesis |
| Associated Diseases | Brain Atrophy, developmental_regression, Developmental Regression, epilepsy, neurodegeneration |
| Interactions | AUTOPHAGY, FERROPTOSIS, LC3B, MITOCHONDRIA, NEURODEGENERATION, WDR45 |
| KG Connections | 44 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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