| Gene Symbol | ALK |
| Aliases | ALKPROTEIN |
| Molecular Weight | 200 kDa |
| Pathways | PI3K, MAPK |
| GeneCards | ALK |
| Human Protein Atlas | ALK |
| Extracellular domain | Mam domain for ligand binding (with identified ligand pleiotrophin) |
| Transmembrane helix | Single pass |
| Juxtamembrane region | Contains activation loop |
| Kinase domain | Catalytic tyrosine kinase activity |
| C-terminal tail | Contains multiple phosphorylation sites |
| Neuronal survival | Prevents apoptosis |
| Differentiation | Promotes neuronal maturation |
| Axonal growth | Supports axon guidance |
| Synaptic plasticity | Modulates synaptic function |
| Associated Diseases | ALS |
| Interactions | EGFR, IRF2BP2, KRAS, YAP |
| KG Connections | 18 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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