| Gene Symbol | PCDH15 |
| Full Name | Protocadherin 15 |
| Chromosome | 10q21.1 |
| Protein Type | Gene |
| Function | is a member of the cadherin superfamily of cell adhesion molecules that plays critical roles in the development and maintenance of the auditory and vestibular systems. |
| Primary Expression | the stereocilia (hair bundle) of inner and outer hair cells in the cochlea - Vestibular system: Present in hair cells of the utricle, saccule, and |
| Subcellular Localization | the tips of stereocilia where mechanotransduction occurs |
| Molecular Weight | 250 kDa |
| Amino Acids | 307 aa |
| Exons | 35 |
| NCBI Gene ID | 65217 |
| GeneCards | PCDH15 |
| Human Protein Atlas | PCDH15 |
| Signal peptide | N-terminal 25 amino acids for secretory pathway targeting |
| Protocadherin repeats | 11 extracellular cadherin (EC) domains, each approximately 110 amino acids, containing conserved calcium-binding motifs (DXNDN, DRE, DXD) at inter-domain boundaries |
| Associated Diseases | neurodegeneration |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
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