concept

NUP85

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NUP85: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

0Analyses

11Outgoing

2Incoming

0Experiments

0Debates

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💡 Concept Info

Name	NUP85
Related Diseases	Fat Disorder, Hepatic Fat Accumulation, NAFLD
Related Pathways	lipid metabolism, PI3K/AKT, PI3K/AKT Signaling Pathway

Pathway Diagram

graph TD
    NUP85[NUP85]
    NUP85 -->|involved_in| NAFLD[NAFLD]
    NUP85 -->|modulates| PI3K_AKT_Signaling_Pathway[PI3K/AKT Signaling Pathway]
    NUP85 -->|downregulates| Hepatic_Fat_Accumulation[Hepatic Fat Accumulation]
    NUP85 -->|upregulates| Fat_Disorder[Fat Disorder]
    NUP85 -->|regulates| Lipid_Metabolism[Lipid Metabolism]
    NUP85 -->|regulates| Inflammation[Inflammation]
    NUP85 -->|regulates| Triglyceride[Triglyceride]
    NUP85 -->|regulates| PI3K_AKT[PI3K/AKT]
    NUP85 -->|participates in| lipid_metabolism[lipid metabolism]
    Mcd_Diet[Mcd Diet] -->|upregulates| NUP85
    benchmark_ot_ad_answer_key_NUP[benchmark_ot_ad_answer_key:NUP85] -->|data_in| NUP85

Outgoing (11)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:NUP85	data_in	dataset_row	0.00
NAFLD	associated_with	disease	0.95
PI3K/AKT Signaling Pathway	modulates	pathway	0.90
Lipid Metabolism	regulates	process	0.85
Inflammation	regulates	process	0.85
Hepatic Fat Accumulation	downregulates	phenotype	0.85
Fat Disorder	downregulates	phenotype	0.85
Fat Disorder	upregulates	phenotype	0.85
Triglyceride	regulates	compound	0.80
PI3K/AKT	regulates	pathway	0.80
lipid metabolism	participates_in	pathway	0.60

Incoming (2)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:NUP85	data_in	dataset_row	0.00
Mcd Diet	upregulates	compound	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NUP85 in their description or question text

No additional research found