| Gene Symbol | ent-gene-173851ef |
| Backsplicing | The 5' end of an exon connects to the 3' end of the same or a different exon |
| Covalent closure | Forms a stable covalently closed circular molecule |
| No cap/tail | Produces circular molecules lacking 5' caps and 3' tails |
| CDR1as (ciRS-7) | Contains 74 miR-7 binding sites, acts as an effective miR-7 sponge[@piwecka2017] |
| Sry circRNA | Contains 16 miR-135 binding sites[@hansen2013a] |
| circHIPK3 | Sponges multiple miRNAs including miR-124 |
| RNA binding protein (RBP) sequestration | Bind and sequester RBPs |
| Transcription factor interference | Trap transcription factors |
| Splicing factor modulation | Affect spliceosome function |
| Internal ribosome entry sites (IRES) | Enable cap-independent translation |
| circRNA-encoded peptides | Produce novel protein isoforms |
| Disease association | Translation products linked to disease states[@pamudurti2017] |
| RNA polymerase II regulation | Modulate transcriptional activity |
| Epigenetic modifications | Affect chromatin modifications |
| Parent gene expression | Regulate expression of host genes |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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