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mechanism 1,629 words KG: Retromer Complex
Contents

Retromer Complex

⚙ Mechanism Info
NameRetromer Complex
Key Genes/ProteinsRAB7A, VPS35
Linked Hypotheses1 hypotheses

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82Vagal Afferent Microbial Signal Modulation
Score: 0.62Lysosomal Enzyme Trafficking Correction
Score: 0.71Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69Vocal Cord Neuroplasticity Stimulation
Score: 0.52Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (29)

What are the mechanisms by which gut microbiome dysbiosis in
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neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne
validation · completed · Score: 0.40

Knowledge Graph (6 edges)

Retromer Complex involved_in Protein Trafficking
Retromer Complex involved_in Tau Pathobiology
RAB7A interacts_with Retromer Complex
VPS35 component_of Retromer Complex
Retromer Complex regulates Endolysosomal System
Retromer Complex mediates Receptor Recycling

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