concept

HOXB13

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HOXB13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

0Analyses

17Outgoing

7Incoming

0Experiments

0Debates

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💡 Concept Info

Name	HOXB13
Key Genes/Proteins	AND, App, AR, CANCER, HDAC3, Raf
Related Diseases	Als, ALS, Cancer, Prostate Cancer, Tumor
Related Pathways	Epigenetic, epigenetic regulation, oxidative stress response

Pathway Diagram

graph TD
    HOXB13["HOXB13"]
    HOXB13 -->|"risk_factor_for"| Prostate_Cancer["Prostate Cancer"]
    HOXB13 -->|"encodes"| G84E["G84E"]
    HOXB13 -->|"inhibits"| Als["Als"]
    HOXB13 -->|"regulates"| Cancer["Cancer"]
    HOXB13 -->|"inhibits"| Tumor["Tumor"]
    HOXB13 -->|"inhibits"| ALS["ALS"]
    HOXB13 -->|"inhibits"| HDAC3["HDAC3"]
    HOXB13 -->|"inhibits"| Epigenetic["Epigenetic"]
    HDAC3 -->|"interacts"| HOXB13
    AND["AND"] -->|"inhibits"| HOXB13

Outgoing (17)

Target	Relation	Type	Str
Prostate Cancer	risk_factor_for	disease	0.90
G84E	encodes	biomarker	0.85
oxidative stress response	participates_in	pathway	0.70
ALS	inhibits	disease	0.65
Tumor	inhibits	disease	0.65
Cancer	associated_with	disease	0.65
Als	inhibits	disease	0.65
Cancer	regulates	disease	0.65
HDAC3	inhibits	gene	0.60
Epigenetic	inhibits	pathway	0.60
App	associated_with	protein	0.60
CANCER	associated_with	gene	0.60
CANCER	regulates	gene	0.60
Raf	activates	protein	0.60
epigenetic regulation	participates_in	pathway	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
App	inhibits	protein	0.60

Incoming (7)

Source	Relation	Type	Str
AR	regulates	gene	0.60
AR	activates	gene	0.60
HDAC3	activates	gene	0.60
AND	associated_with	gene	0.60
HDAC3	interacts_with	protein	0.60
HDAC3	inhibits	gene	0.60
AND	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning HOXB13 in their description or question text

No additional research found