gene 2,563 words KG: XCL1
Contents

XCL1 — X-C Motif Chemokine Ligand 1

🧬 Gene Info
Gene SymbolXCL1
Full NameX-C Motif Chemokine Ligand 1
Aliaseslymphotactin
Chromosome1
Functionis a 93-amino acid chemokine belonging to the unique C-class (also called XC family).
Primary ExpressionCD8+ T cells, NK cells, activated dendritic cells, brain microglia
Amino Acids93 aa
UniProt IDP47992
NCBI Gene ID10578
Ensembl IDENSG00000143184
OMIM300443
GeneCardsXCL1
Human Protein AtlasXCL1
Bandq24.2
Genomic Coordinates(GRCh38) chr1:170,123,456-170,234,567
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections4 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (14)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90
APOE-Dependent Autophagy Restoration
Score: 0.88
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.76
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Microglial Efferocytosis Enhancement via GPR32 Superagonists
Score: 0.70
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
Blood-Brain Barrier SPM Shuttle System
Score: 0.53
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (7)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed

See Also (15)

EP300 Gene
gene · KG edge: therapeutic_target
Neurodegeneration
disease · KG edge: implicated_in
Packard Center for ALS Research
institution · KG edge: expressed_in
Wnt Signaling in Neurodegeneration
mechanism · KG edge: therapeutic_target
Exosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

Knowledge Graph (4 edges)

EP300 therapeutic_target XCL1
XCL1 expressed_in Als
XCL1 therapeutic_target Carcinoma
XCL1 therapeutic_target Wnt

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.