gene 1,138 words KG: TMEM
Contents

TMEM163 Gene

🧬 Gene Info
Gene SymbolTMEM
AliasesTMEM
Functionplays important roles in cellular homeostasis, protein quality control, and signal transduction
InteractionsAND
KG Connections9 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.79
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Microglial Purinergic Reprogramming
Score: 0.70
Targeted Butyrate Supplementation for Microglial Phenotype M
Score: 0.70
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
VCP-Mediated Autophagy Enhancement
Score: 0.59
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43

Related Analyses (12)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (3)

Neurodegeneration
disease · KG edge: implicated_in
TOLLIP — Toll-Interacting Protein
gene · KG edge: regulates
VCP Proteostasis Modulation Therapy for ALS/FTD
idea · KG edge: regulates

Knowledge Graph (9 edges)

TOLLIP regulates TMEM
TMEM regulates VCP
VCP regulates TMEM
CANCER therapeutic_target TMEM
TMEM therapeutic_target Cancer
genes-tmem linked_to TMEM
TMEM data_in benchmark_ot_ad_answer_key:TMEM
benchmark_ot_ad_answer_key:TMEM data_in TMEM
AND activates TMEM

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