gene 1,293 words KG: SYNA
Contents

SYNA — Synapsin I

🧬 Gene Info
Gene SymbolSYNA
Full NameSynapsin I
Chromosome17q21.31
Functionis a neuronal phosphoprotein associated with the cytoplasmic surface of synaptic vesicles.
Primary ExpressionBrain (cortex, hippocampus, cerebellum), neurons
Subcellular Localizationpresynaptic terminals where it associates with the cytoplasmic surface of synaptic vesicles. [@takamori2006]
Amino Acids706 aa
UniProt IDP17600
NCBI Gene ID6853
Ensembl IDENSG00000135547
OMIM313440
GeneCardsSYNA
Human Protein AtlasSYNA
Synapsin Ia706 amino acids
Synapsin Ib669 amino acids (lacking domain E)
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (30)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.76
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69

Related Analyses (30)

Synaptic pruning by microglia in early AD
neurodegeneration · completed
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (14)

Microglia
cell · KG edge: co_discussed
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: co_discussed
Neurodegeneration
disease · KG edge: implicated_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: co_discussed
Microglia in Neurodegeneration
entity · KG edge: co_discussed

Knowledge Graph (12 edges)

TFEB binds_to SYNA
SYNA co_discussed SPP1
SYNA co_discussed DYSF
GNAL co_discussed SYNA
SYNA co_discussed C1QA
SYNA co_discussed GRN
SYNA co_discussed CTSB
COMPLEMENT CASCADE co_discussed SYNA
C1Q co_discussed SYNA
MICROGLIA co_discussed SYNA

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