gene 2,540 words KG: SRSF3
Contents

SRSF3 Gene

🧬 Gene Info
Gene SymbolSRSF3
Full NameSerine/Arginine-Rich Splicing Factor 3
Chromosome6p21.33
Functionis an essential RNA-binding protein that plays critical roles in pre-mRNA splicing, alternative splicing regulation, mRNA export, and translation.
Molecular Weight19 kDa
Amino Acids248 aa
Exons4
PathwaysRna Splicing
UniProt IDP84104
NCBI Gene ID6734
Ensembl IDENSG00000161547
GeneCardsSRSF3
Human Protein AtlasSRSF3
Associated DiseasesALS
InteractionsALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS, ASTROCYTE, ASTROCYTES
KG Connections27 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (8)

Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Liquid-Liquid Phase Separation Modifier Therapy
Score: 0.55
Cryptic Exon Silencing Restoration
Score: 0.53
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Astrocytes
cell · KG edge: activates
Amyotrophic Lateral Sclerosis
redirect · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Astrocytes
entity · KG edge: activates
NGF (Redirect)
redirect · KG edge: activates

Knowledge Graph (12 edges)

NGF activates SRSF3
SRSF1 co_expressed_with SRSF3
SRSF2 co_expressed_with SRSF3
HNRNPA1 associated_with SRSF3
HNRNPA2B1 associated_with SRSF3
SRSF1 associated_with SRSF3
SRSF2 associated_with SRSF3
NEUROTOXICITY activates SRSF3
NEURODEGENERATION activates SRSF3
CYTOKINES activates SRSF3

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