gene 2,514 words KG: SIGLEC10
Contents

SIGLEC10 — Sialic Acid Binding Ig-Like Lectin 10

🧬 Gene Info
Gene SymbolSIGLEC10
Full NameSialic Acid Binding Ig-Like Lectin 10
Chromosome19q13.4
Functionis a member of the Siglec family of cell surface lectins that recognize sialic acid residues on glycoconjugates.
Primary ExpressionB cells, monocytes, eosinophils, dendritic cells
Molecular Weight60 kDa
Amino Acids553 aa
Exons12
UniProt IDQ9H7M1
NCBI Gene ID89792
GeneCardsSIGLEC10
Human Protein AtlasSIGLEC10
Associated DiseasesGlioma
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (2)

Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.98
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (6)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (6 edges)

SIGLEC10 mediates Tumor Immune Escape
ITGA3 binds SIGLEC10
SIGLEC10 inhibits Macrophage Phagocytosis
SIGLEC10 associated_with Glioma
CD24 binds SIGLEC10
ITGB1 binds SIGLEC10

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