gene 1,336 words KG: PPP1R7
Contents

PPP1R7 — SDS22 (Protein Phosphatase 1 Regulatory Subunit 7)

🧬 Gene Info
Gene SymbolPPP1R7
Full NameSDS22 (Protein Phosphatase 1 Regulatory Subunit 7)
Chromosome2q33.1
Protein TypePhosphatase
FunctionPPP1 regulatory subunit, cell cycle regulation
Primary Expressionvarious tissues with particularly high levels in:
Subcellular Localization**Cytoplasm**: Primary localization in the cytoplasm
Amino Acids382 aa
Exons14
UniProt IDQ86X55
NCBI Gene ID5509
Ensembl IDENSG00000173457
GeneCardsPPP1R7
Human Protein AtlasPPP1R7
BrainCerebral cortex, hippocampus, cerebellum, substantia nigra
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsATP, Ras
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (2)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Down Syndrome Alzheimer's Disease: Mechanisms and Therapeuti
clinical · proposed · Score: 0.40

See Also (10)

ATP P2X3 Receptor Neurons
cell · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: associated_with
COX15 — Cytochrome C Oxidase Assembly Factor 15
gene · KG edge: associated_with
PEX3 Gene - Peroxisome Biogenesis Factor 3
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PPP1R7 co_expressed_with SDS22
PPP1R7 co_expressed_with STK25
PPP1R7 co_expressed_with PASKIN
PPP1R7 biomarker_for FOLFOX
PPP1R7 associated_with ABCB1
PPP1R7 associated_with PEX3
PPP1R7 associated_with VPS33A
PPP1R7 associated_with VPS16
PPP1R7 associated_with COX15
PPP1R7 associated_with RPL4

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