| Gene Symbol | PHOX2B |
| Full Name | Paired Homeobox 2B |
| Chromosome | 4p13 |
| Protein Family | Paired homeobox transcription factors |
| Protein Type | Transcription Factor |
| Function | encodes a critical transcription factor that serves as a master regulator of autonomic nervous system (ANS) development. |
| Primary Expression | dopaminergic neurons of the substantia nigra pars compacta, a region critically affected in [Parkinson's disease](/ |
| Amino Acids | 314 aa |
| UniProt ID | Q75WG7 |
| NCBI Gene ID | 9088 |
| Ensembl ID | ENSG00000178363 |
| OMIM | 603851 |
| GeneCards | PHOX2B |
| Human Protein Atlas | PHOX2B |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| KG Connections | 21 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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