| Gene Symbol | PCK2 |
| Chromosome | 14q12 |
| Protein Type | Gene |
| Function | Phosphoenolpyruvate carboxykinase 2 (PCK2) is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate (PEP), a rate-limiting step in gluconeogenesis and anaplerosis |
| Primary Expression | tissues with high gluconeogenic activity including liver, kidney, and brain |
| Amino Acids | 640 aa |
| UniProt ID | Q16822 |
| GeneCards | PCK2 |
| Human Protein Atlas | PCK2 |
| Associated Diseases | neurodegeneration |
| Interactions | AMPK, MTOR, PARKIN |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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