| Gene Symbol | MAP2K5 |
| Aliases | MAP2K5 (MEK5) |
| Function | The MEK5 protein consists of 471 amino acids and contains a kinase domain with characteristic motifs required for dual-specificity phosphorylation. |
| Amino Acids | 471 aa |
| Pathways | MAPK |
| Ensembl ID | ENSG00000108691 |
| GeneCards | MAP2K5 |
| Human Protein Atlas | MAP2K5 |
| Growth factors | BDNF, NGF, EGF |
| Cellular stress | Oxidative stress, endoplasmic reticulum stress |
| Synaptic activity | Glutamate receptor activation |
| Inflammatory signals | Cytokine signaling in glia |
| MEF2 family | Myocyte enhancer factor 2 (MEF2A-D) |
| CREB | cAMP response element-binding protein |
| c-Fos | Immediate early gene product |
| Associated Diseases | neurodegeneration |
| Interactions | ALS |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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