gene 591 words KG: LAMP5
Contents

LAMP5 Gene — Lysosomal Associated Membrane Protein 5

🧬 Gene Info
Gene SymbolLAMP5
Full NameLAMP5 — Lysosomal Associated Membrane Protein 5
AliasesLysosomal Associated Membrane Protein 5
Chromosome20p13.
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionneurons and has been implicated in Alzheimer's disease susceptibility through genome-wide association studies
Molecular Weight45 kDa
Amino Acids299 aa
Pathwaysoxidative stress response
GeneCardsLAMP5
Human Protein AtlasLAMP5
Associated DiseasesALS, Alzheimer
KG Connections23 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (11)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Membrane Cholesterol Gradient Modulators
Score: 0.71
Lysosomal Enzyme Trafficking Correction
Score: 0.71
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (8)

NeuRon Therapeutics
company · KG edge: associated_with
Neurodegeneration
disease · KG edge: implicated_in
Neurons
entity · KG edge: expressed_in
Genes
index · KG edge: expressed_in
PVALB Gene - Parvalbumin
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PVALB associated_with LAMP5
LAMP5 associated_with SST
SST associated_with LAMP5
LAMP5 associated_with PVALB
LAMP5 co_expressed_with PVALB
LAMP5 co_expressed_with SST
ALZHEIMER expressed_in LAMP5
RNA expressed_in LAMP5
NEURON associated_with LAMP5
LAMP5 expressed_in Alzheimer

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