| Gene Symbol | KIF5C |
| Aliases | Neuronal |
| Chromosome | 2q23.3 |
| Function | KIF5C is a neuron-specific kinesin heavy chain that functions in axonal transport. |
| Primary Expression | brain, particularly in cortical neurons |
| Molecular Weight | 109 kDa |
| Pathways | Cargo Transport |
| UniProt ID | Q9P0N2 |
| NCBI Gene ID | 3800 |
| Ensembl ID | ENSG00000154640 |
| GeneCards | KIF5C |
| Human Protein Atlas | KIF5C |
| Hereditary Spastic Paraplegia (HSP) | Mutations in KIF1A, KIF5A cause HSP |
| Charcot-Marie-Tooth Disease | KIF1B (CMT2A), KIF1A, KIF5A |
| Alzheimer's Disease | Impaired transport contributes to amyloid and tau pathology |
| Associated Diseases | Intellectual Disability, Cortical Malformations |
| Interactions | HNRNPA2B1, KIF5A, KIF5B, KINESIN-1, Raf, TRAK2 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!