gene 1,699 words KG: IFNAR2
Contents

IFNAR2 — Interferon Alpha Receptor 2

🧬 Gene Info
Gene SymbolIFNAR2
Full NameInterferon Alpha Receptor 2
Chromosome21q22.1
Primary Expressionneurons, microglia, astrocytes, and [oligodendrocytes](/entiti
Amino Acids505 aa
PathwaysJAK-STAT signaling
UniProt ID[P48551](https://www.uniprot.org/uniprot/P48551)
Ensembl IDENSG00000159197
OMIM206550
GeneCardsIFNAR2
Human Protein AtlasIFNAR2
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsALZHEIMER, C1Q, PSEN1, STAT2, VIRAL INFECTIONS
KG Connections36 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (10)

Astrocytes
cell · KG edge: regulates
JAK Inhibitors in Parkinson's Disease
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
Astrocytes
entity · KG edge: regulates
PSEN1 (Redirect)
redirect · KG edge: regulates

Knowledge Graph (12 edges)

C1Q activates IFNAR2
PSEN1 activates IFNAR2
IFNAR2 regulates C1Q
IFNAR2 regulates TNF
IFNAR2 expressed_in STAT2
IFNAR2 regulates PSEN1
C1Q regulates IFNAR2
PSEN1 regulates IFNAR2
STAT2 expressed_in IFNAR2
STAT2 inhibits IFNAR2

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