gene 1,566 words KG: EGR4
Contents

EGR4

🧬 Gene Info
Gene SymbolEGR4
AliasesEarly Growth Response 4
Chromosome2p13.3
Protein TypeTranscription Factor
Functionis a zinc finger transcription factor and member of the EGR (Early Growth Response) family of immediate-early genes.
Molecular Weight54 kDa
Amino Acids476 aa
Ensembl IDENSG00000186866
GeneCardsEGR4
Human Protein AtlasEGR4
Associated DiseasesAls, Cancer, Glioblastoma, Ms, Tumor
InteractionsBdnf, BDNF, FOSB, MICROGLIA, Raf
KG Connections25 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Brain Connectivity-Targeted tACS Trial in Early AD
clinical · proposed · Score: 0.51
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Biomarker-Guided Sequential Therapy Selection in Alzheimer's
clinical · proposed · Score: 0.40

See Also (11)

Microglia
cell · KG edge: activates
NeuRon Therapeutics
company · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Microglia in Neurodegeneration
entity · KG edge: activates
BDNF Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

PTEN associated_with EGR4
EGR4 associated_with EGFR
EGR4 associated_with CDKN2A
EGR4 associated_with GBM
CDKN2A associated_with EGR4
GBM associated_with EGR4
EGFR associated_with EGR4
FOSB activates EGR4
BDNF activates EGR4
EGR4 activates BDNF

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.