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gene 767 words KG: CPSF6
Contents

CPSF6 — Cleavage and Polyadenylation Specific Factor 6

🧬 Gene Info
Gene SymbolCPSF6
Full NameCleavage and Polyadenylation Specific Factor 6
FunctionCPSF6 encodes a component of the cleavage and polyadenylation specificity factor (CPSF) complex, which is essential for mRNA 3'-end processing.
UniProt IDCPSF6
Ensembl IDENSG00000149596
GeneCardsCPSF6
Human Protein AtlasCPSF6
mRNA processingComponent of the CFII complex for 3'-end cleavage and polyadenylation
RNA splicingRegulates alternative splicing of specific transcripts
Stress responseLocalizes to stress granules under cellular stress
Chromatin regulationAssociates with chromatin in neuronal nuclei
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (8)

Purinergic Signaling Polarization Control
Score: 0.71Mechanosensitive Ion Channel Reprogramming
Score: 0.70Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67Cross-Seeding Prevention Strategy
Score: 0.69Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65Glycine-Rich Domain Competitive Inhibition
Score: 0.64Cryptic Exon Silencing Restoration
Score: 0.53RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_inAlpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypothesesIL-6 (Interleukin-6) in Neurodegeneration
biomarker · Pages share 3 hypothesesCell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypothesesExosomal Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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