gene 1,490 words KG: ATP2A2
Contents

ATP2A2 Gene

🧬 Gene Info
Gene SymbolATP2A2
Full NameATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2
AliasesSERCA2 calcium pump, SERCA2
Chromosome12q24.11
Protein FamilyP-type ATPase family (ion transport)
FunctionThis process is crucial for
Primary ExpressionUbiquitous, high in brain, heart, skeletal muscle
Molecular Weight110 kDa
Amino Acids12 aa
PathwaysAutophagy, Immune Response
UniProt IDQ93014
NCBI Gene ID488
GeneCardsATP2A2
Human Protein AtlasATP2A2
ER calcium homeostasisMaintains high ER calcium concentrations (100-500 μM vs. ~100 nM cytosolic)
Associated Diseasesneurodegeneration
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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