gene 863 words KG: ADCY8
Contents

ADCY8 Gene

🧬 Gene Info
Gene SymbolADCY8
Full NameAdenylate Cyclase 8
Chromosome8q24.22
FunctionADCY8 plays essential roles in neuronal physiology:
Molecular Weight125 kDa
Exons28
GeneCardsADCY8
Human Protein AtlasADCY8
N-terminal extracellular domainContains glycosylation sites
Transmembrane region (M1-M6)Forms the membrane-spanning core
Calmodulin-binding domainLocated in the C-terminal cytoplasmic region
Cerebral cortexLayer-specific expression in pyramidal neurons
CerebellumEnriched in Purkinje cells
AmygdalaModulates emotional memory
Subcortical structuresPresent in basal ganglia and thalamus
Associated Diseaseslong_term_spatial_memory_formation, migratory distance
KG Connections19 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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