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Dataset: oasis
dataset
535 words
KG: Alzheimer's disease
Contents
oasis
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Knowledge Graph
Related Hypotheses (9)
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
APOE Isoform Conversion Therapy
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Show 4 more
Related Analyses (7)
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · completed
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Neuroinflammation and microglial priming in early Alzheimer'
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
Show 2 more
Related Experiments (3)
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Sex Differences in Alzheimer's Disease — mechanisms and ther
clinical · proposed · Score: 0.40
Knowledge Graph (12 edges)
DNAJB6
associated_with
Alzheimer's disease
cGAS-STING pathway
associated_with
Alzheimer's disease
gut microbiota
associated_with
Alzheimer's disease
insulin resistance
associated_with
Alzheimer's disease
DRP1
associated_with
Alzheimer's disease
SIRT1
associated_with
Alzheimer's disease
SMPD1
associated_with
Alzheimer's disease
SNCA
associated_with
Alzheimer's disease
LRRK2
associated_with
Alzheimer's disease
senescent microglia
associated_with
Alzheimer's disease
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