clinical_trial 964 words KG: ROCK
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Fasudil for Parkinson's Disease (ROCK-PD)

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Related Hypotheses (3)

Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38

Related Analyses (10)

TREM2 Therapeutic Strategy Post-INVOKE-2
neurodegeneration · completed
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Gut-Brain Axis Therapeutics for AD
neurodegeneration · completed
TREM2 agonism vs antagonism in DAM microglia
neurodegeneration · completed
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · completed

Related Experiments (30)

TREM2 Agonist Therapy for Parkinson's Disease — Experimental
validation · proposed · Score: 0.45
AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
AAV Serotype Comparison for LRRK2 Knockdown in PD
validation · proposed · Score: 0.40
Alpha-Synuclein SAA Kinetics Study — Biological Staging Back
clinical · proposed · Score: 0.40
Alpha-Synuclein Aggregation Triggers — Sporadic PD Initiatio
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

ROCK activates PI3K
Y27632 inhibits ROCK
ROCK promotes Axon Regeneration
ROCK promotes Schwann Cell Proliferation
GAP43 activates ROCK
GAP43 regulates ROCK
MLCK inhibits ROCK
ROCK activates neurodegeneration
LC3 inhibits ROCK
ROCK inhibits WIPI1

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