biomarker 1,032 words KG: ent-gene-62458d07
Contents

VMAT2 - Dopaminergic Biomarker

🔬 Protein Info
Gene SymbolVMAT2
Full NameBiomarker
Chromosome10q25.2
FunctionVMAT2 mediates vesicular uptake of monoamines
Primary Expressionall monoaminergic neurons (dopaminergic, serotonergic, noradrenergic)
Molecular Weight56 kDa
Amino Acids525 aa
Exons18
PathwaysAutophagy, Mapk, Mtor
NCBI Gene ID6844
Ensembl IDENSG00000165646
OMIM193001
GeneCardsVMAT2
Human Protein AtlasVMAT2
High expressionSubstantia nigra pars compacta (dopaminergic neurons), locus coeruleus (noradrenergic neurons), dorsal raphe (serotonergic neurons)
Associated DiseasesParkinson's disease
Known Drugs/Compoundslevodopa
InteractionsALPHA-SYNUCLEIN, AMPK, AUTOPHAGY, DAT, MTOR, NEUROINFLAMMATION
KG Connections28 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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