| Gene Symbol | PTAU181 |
| Chromosome | 17q21 |
| GeneCards | PTAU181 |
| Human Protein Atlas | PTAU181 |
| CDK5 (Cyclin-Dependent Kinase 5) | Neuron-specific kinase activated in AD |
| Japanese cohorts | AUC 0.89-0.93 for AD vs. controls [@japanese2022] |
| Chinese cohorts | AUC 0.87-0.92, with similar cutoff values to Western populations [@chinese2023] |
| Korean cohorts | AUC 0.90-0.95, p-tau 181 successfully distinguishes AD from MCI [@korean2023] |
| Associated Diseases | Alzheimer's Disease, CSF, ALS |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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