| Gene Symbol | ent-prot-b65d5156 |
| Subcellular Localization | Astrocytic end-feet (perivascular), ependymal cells |
| Molecular Weight | ~30 kDa (monomer), forms tetramers |
| Gene | AQP4 |
| Structure | Six transmembrane alpha-helices with N- and C-termini intracellular |
| M1 isoform | Full-length protein |
| Waste clearance | Removes metabolic waste products (Aβ, tau, lactate) |
| CSF circulation | Facilitates cerebrospinal fluid movement |
| Brain edema regulation | Controls water flux during pathology |
| Ion homeostasis | Maintains brain osmotic balance |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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