| Gene Symbol | Alpha-Synuclein Oligomers |
| Spherical oligomers | Most common; 5-20 nm diameter |
| Annular oligomers | Pore-like structures that may disrupt membranes |
| Protofibrils | Elongated intermediates that mature into fibrils |
| Phosphorylated oligomers | Species with serine-129 phosphorylation (pathological marker) |
| Diagnostic utility | Distinguishing synucleinopathies from non-synuclein diseases |
| Disease progression | Correlating oligomer levels with disease severity |
| Therapeutic monitoring | Measuring response to disease-modifying therapies |
| Prodromal detection | Identifying individuals before clinical diagnosis |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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