protein

CRY1-PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CRY1-PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

CRY1 Protein

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🔬 Protein Info

Gene Symbol	CRY1
Full Name	PROTEIN
Chromosome	12q24.31
Function	Transcriptional Activation: CLOCK and BMAL1 proteins form a heterodimer that activates transcription of period (PER) and cryptochrome (CRY) genes
Primary Expression	Ubiquitous (high in brain, liver, retina)
Molecular Weight	66 kDa
Amino Acids	500 aa
Pathways	Akt, Circadian Rhythm, Lipid Metabolism, Mtor, Nf-Κb
UniProt ID	Q9UQL6
NCBI Gene ID	1399
Ensembl ID	ENSG00000012048
OMIM	601033
GeneCards	CRY1
Human Protein Atlas	CRY1
Associated Diseases	Als, Depression, Stroke
Interactions	AKT, AMPK, ANXIETY, App, APP, BDNF
KG Connections	214 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CRY1-PROTEIN — AlphaFold Q9UQL6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Pathway Diagram

graph TD
    A["Gene expression"] --> B["CRY1 PROTEIN"]
    B --> C["Protein folding and
quality control"]
    B --> D["Cellular signaling"]
    C --> E["Proteostasis"]
    D --> F["Neurotoxicity"]
    E --> G["Disease outcome"]
    F --> G
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class B protein
    class G disease

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CRY1-PROTEIN in their description or question text

No additional research found