Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HEPATIC STEATOSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | HEPATIC STEATOSIS |
graph TD
HEPATIC_STEATOSIS[HEPATIC STEATOSIS]
Metformin[Metformin] -->|treats| HEPATIC_STEATOSIS
Macrophage_STING_YAP_Axis[Macrophage STING-YAP Axis] -->|regulates| HEPATIC_STEATOSIS
Arsenic[Arsenic] -->|causes| HEPATIC_STEATOSIS
Nuciferine[Nuciferine] -->|treats| HEPATIC_STEATOSIS
Free_Fatty_Acid_Bile_Acid_mTOR[Free Fatty Acid/Bile Acid-mTOR-FXR/PPARα Signaling] -->|mediates| HEPATIC_STEATOSIS
Free_Fatty_Acid_Bile_Acid_MTOR[Free Fatty Acid/Bile Acid-MTOR-FXR/PPARA Signaling] -->|regulates| HEPATIC_STEATOSIS
JNK1[JNK1] -->|regulates| HEPATIC_STEATOSIS
Hesperetin[Hesperetin] -->|treats| HEPATIC_STEATOSIS
CHKA[CHKA] -->|suppresses| HEPATIC_STEATOSIS
CHKB[CHKB] -->|suppresses| HEPATIC_STEATOSIS| Target | Relation | Type | Str |
|---|---|---|---|
| extracellular vesicles | associated_with | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Macrophage STING-YAP Axis | regulates | pathway | 0.95 |
| Arsenic | causes | compound | 0.95 |
| Metformin | treats | drug | 0.95 |
| Reduced Phosphatidylcholine | biomarker_for | phenotype | 0.90 |
| CHKA | suppresses | gene | 0.90 |
| CHKB | suppresses | gene | 0.90 |
| Autophagy | regulates | process | 0.90 |
| Free Fatty Acid/Bile Acid-MTOR-FXR/PPARA Signaling | regulates | pathway | 0.90 |
| Nuciferine | treats | drug | 0.90 |
| Free Fatty Acid/Bile Acid-mTOR-FXR/PPARα Signaling | mediates | pathway | 0.90 |
| JNK1 | regulates | gene | 0.90 |
| Hesperetin | treats | compound | 0.90 |
| AMPK | involved_in | gene | 0.85 |
| Phosphatidylcholine | protects_against | compound | 0.85 |
| Mi-891 | treats | drug | 0.85 |
| AMPK | protects_against | protein | 0.85 |
| QGJZF | associated_with | drug | 0.80 |
| DNA Methyltransferase Inhibitors | treats | drug | 0.80 |
| lycorine | treats | drug | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HEPATIC STEATOSIS in their description or question text
No additional research found