Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about calcium influx: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Mitochondrial ROS Accumulation | causes | process | 0.85 |
| Macrophage Function | regulates | phenotype | 0.80 |
| MECHANOSENSITIVE ION CHANNELS | involved_in | receptor | 0.80 |
| tau release | activates | mechanism | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PIEZO1 | mediates | protein | 0.90 |
| KCNK2 | modulates | gene | 0.90 |
| PIEZO1 | causes | protein | 0.90 |
| TRPC6 | causes | protein | 0.90 |
| KCNK2 | inhibits | gene | 0.85 |
| Substrate Stiffness | promotes | phenotype | 0.85 |
| Tissue Stiffness | upregulates | phenotype | 0.80 |
| Soluble Signals | modulates | compound | 0.75 |
| NMDAR overactivation | causes | mechanism | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-04 | 7 hypotheses Top: 0.640
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning calcium influx in their description or question text
No additional research found