Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ASPIRIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ASPIRIN |
| Related Diseases | ATHEROSCLEROSIS, METASTASIS, STROKE |
graph TD
ASPIRIN[ASPIRIN]
ASPIRIN -->|inhibits| CYCLOOXYGENASE[CYCLOOXYGENASE]
ASPIRIN -->|inhibits| Platelet_Activation[Platelet Activation]
ASPIRIN -->|inhibits| NF__B[NF-κB]
ASPIRIN -->|activates| FOXG1[FOXG1]
ASPIRIN -->|treats| presbycusis[presbycusis]
ASPIRIN -.protects against.-> METASTASIS[METASTASIS]
ASPIRIN -->|treats| neuroinflammation[neuroinflammation]
ASPIRIN -->|activates| purinergic_receptor[purinergic receptor]| Target | Relation | Type | Str |
|---|---|---|---|
| CYCLOOXYGENASE | inhibits | enzyme | 0.90 |
| NF-κB | inhibits | pathway | 0.90 |
| Platelet Activation | inhibits | process | 0.90 |
| Neuroinflammation | associated_with | process | 0.85 |
| FOXG1 | activates | gene | 0.70 |
| presbycusis | treats | disease | 0.70 |
| METASTASIS | protects_against | phenotype | 0.65 |
| neuroinflammation | treats | disease | 0.60 |
| purinergic receptor | activates | receptor | 0.60 |
| purinergic receptor | inhibits | receptor | 0.60 |
| STROKE | associated_with | disease | 0.50 |
| ATHEROSCLEROSIS | associated_with | disease | 0.45 |
| METASTASIS | associated_with | phenotype | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ATHEROSCLEROSIS | associated_with | disease | 0.45 |
| METASTASIS | associated_with | phenotype | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ASPIRIN in their description or question text
No additional research found