entity

VIP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VIP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections
1Hypotheses
1Analyses
3Outgoing
6Incoming
0Experiments
4Debates

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Wiki Pages (9)

Knowledge base pages for this entity

Canonical Page

VIP-Positive Cortical Interneurons

cell · 1302 words

VIP-Positive Hippocampal Interneurons

cell · 1988 words

Cortical Vasoactive Intestinal Peptide (VIP) Neurons

cell · 1840 words

Suprachiasmatic Nucleus VIP Neurons

cell · 1432 words

Vasoactive Intestinal Peptide (VIP+) Interneurons

cell · 1164 words

Cortical VIP Disinhibitory Neurons

cell · 920 words

Outgoing (3)

TargetRelationTypeStr
pyramidal neuronsmodulatescell_type0.80
neuroscienceassociated_withdisease0.50
VIP_interneuronsexpressed_incell_type0.50

Incoming (6)

SourceRelationTypeStr
h-a635d4e5targetshypothesis0.55
CAMK2Aco_associated_withgene0.40
CHATco_associated_withgene0.40
MAPTco_associated_withgene0.40
GRIN2Bco_associated_withgene0.40

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Default Mode Network Circuit Stabilization 0.627 neuroscience Circuit-level neural dynamics in neurode

Mentioning Analyses (1)

Scientific analyses that reference this entity

Circuit-level neural dynamics in neurodegeneration

neuroscience | 2026-04-03 | 66 hypotheses Top: 1.000

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (11)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Plasma lipidomic fingerprinting enables high-accuracy biomarker discovery for Al [PMID:40579668] Gao X, Cheng X, Chen P, Lin L, Wang X et Geroscience 2026 0
Neuronal feedback loop of the suprachiasmatic nucleus generates robust circadian [PMID:41486279] Wang M, Tsuno Y, Peng Y, Islam MT, Matsu Nat Commun 2026 0
Effect of Physical Activity on Cognitive Function of Patients With Alzheimer's D [PMID:41609036] Dai S, Yuan S, Zhang X, Zhong X, Jiang C J Integr Neurosci 2026 0
Neuropeptide-GPCR Regulation of the Neuroimmune Axis in Neurodegeneration: Mecha [PMID:41700028] Zhang X, Bao H, Hu J, Ren W, He Z et al. Bioconjug Chem 2026 0
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis [PMID:41760895] Li J, Chen M, Ren P, Sun G, Zhong F et a NPJ Digit Med 2026 0
Remote robotic surgery: a systematic review. [PMID:41813998] Liu Y, Ma Z, Liu P, Zhu X, Zhao L et al. Surg Endosc 2026 0
Hypothalamic clock governs circadian pain. [PMID:41855333] Wei HR, Lou Q, Li LX, Tang L, Wu RJ et a Science 2026 0
Ginseng for Cognitive Function in Elderly Adults with Mild Cognitive Impairment, [PMID:41863264] Chen N, Yu L, Hua Q, Li B, Zheng X et al Curr Neuropharmacol 2026 0
Comparative efficacy of probiotic, prebiotic, and synbiotic interventions in chi [PMID:41883407] Yang Y, Li Y, Yan X, Huang W, Cao C et a Front Nutr 2026 0
Comparison and Evaluation of Efficacy and Safety of Sitagliptin and Linagliptin [PMID:41918146] Li L, Cui S, Chow J, Wu Y, Yu Q et al. J Evid Based Med 2026 0
Cftr nominates a novel therapeutic target for Alzheimer's disease: Evidence from [PMID:41401902] Li HR, Shi JZ, Zhang MJ, Yun LY, Zhou YF Neuropharmacology 2026 0

Debates (4)

Multi-agent debates referencing this entity

Hypothesis debate: Closed-loop optogenetic targeting PV interneurons to restore

closed · Rounds: 4 · Score: 0.00 · 2026-04-26

Hypothesis debate: Closed-loop transcranial focused ultrasound targeting EC-II S

closed · Rounds: 4 · Score: 0.00 · 2026-04-26

Hypothesis debate: Closed-loop transcranial focused ultrasound with 40Hz gamma e

closed · Rounds: 4 · Score: 0.00 · 2026-04-26

Analyze circuit-level changes in neurodegeneration using Allen Institute Neural

closed · Rounds: 4 · Score: 0.95 · 2026-04-03

Related Research

Hypotheses and analyses mentioning VIP in their description or question text

No additional research found