Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SPINT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SPINT1 |
| Key Genes/Proteins | ADRA2A, CD36, CDC42EP3, FGFRL1, GRAMD1B, MAP1A |
| Related Diseases | Ovarian Cancer |
graph TD
SPINT1[SPINT1]
SPINT1 -->|target for| Ovarian_Cancer[Ovarian Cancer]
SPINT1 -->|modulates| Tumor_Immune_Cell_Activity[Tumor Immune Cell Activity]
SPINT1 -->|data_in| benchmark_ot_ad_answer_key_SPI[benchmark_ot_ad_answer_key:SPINT1]
benchmark_ot_ad_answer_key_SPI -->|data_in| SPINT1| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:SPINT1 | data_in | dataset_row | 0.00 |
| Ovarian Cancer | therapeutic_target | disease | 0.85 |
| Ovarian Cancer | associated_with | disease | 0.85 |
| Tumor Immune Cell Activity | modulates | process | 0.75 |
| XPR1 | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:SPINT1 | data_in | dataset_row | 0.00 |
| ADRA2A | associated_with | gene | 0.60 |
| CD36 | associated_with | gene | 0.60 |
| MAP1A | associated_with | gene | 0.60 |
| NFE2L3 | associated_with | gene | 0.60 |
| SIGLEC11 | associated_with | gene | 0.60 |
| SLC24A4 | associated_with | gene | 0.60 |
| CDC42EP3 | associated_with | gene | 0.60 |
| FGFRL1 | associated_with | gene | 0.60 |
| MYL9 | associated_with | gene | 0.60 |
| GRAMD1B | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SPINT1 in their description or question text
No additional research found