protein

SERINE PALMITOYLTRANSFERASE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SERINE PALMITOYLTRANSFERASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

8Outgoing

7Incoming

0Experiments

0Debates

Summary

Page for Serine Palmitoyltransferase Protein

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🔬 Protein Info

Gene Symbol	SERINE PALMITOYLTRANSFERASE
Molecular Weight	53 kDa
Amino Acids	473 aa
Pathways	Sphingolipid
Interactions	SPTLC1
KG Connections	14 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    SERINE_PALMITOYLTRANSFERASE["SERINE PALMITOYLTRANSFERASE"]
    SERINE_PALMITOYLTRANSFERASE -->|"involved_in"| SPTLC1["SPTLC1"]
    SERINE_PALMITOYLTRANSFERASE -->|"inhibits"| CERAMIDE["CERAMIDE"]
    SERINE_PALMITOYLTRANSFERASE -->|"causes"| Sphingolipid["Sphingolipid"]
    SERINE_PALMITOYLTRANSFERASE -->|"expressed in"| Genes["Genes"]
    SERINE_PALMITOYLTRANSFERASE -->|"interacts"| MONOCYTE["MONOCYTE"]
    SPTLC1 -->|"causes"| SERINE_PALMITOYLTRANSFERASE
    CERS2["CERS2"] -->|"regulates"| SERINE_PALMITOYLTRANSFERASE
    ABCA1["ABCA1"] -->|"regulates"| SERINE_PALMITOYLTRANSFERASE
    SPTLC2["SPTLC2"] -->|"regulates"| SERINE_PALMITOYLTRANSFERASE

Outgoing (8)

Target	Relation	Type	Str
SPTLC1	involved_in	gene	0.60
Sphingolipid	causes	pathway	0.50
Sphingolipid	expressed_in	pathway	0.50
CERAMIDE	regulates	concept	0.50
CERAMIDE	inhibits	concept	0.50
MONOCYTE	interacts_with	concept	0.50
atherosclerosis	inhibits	disease	0.50
Sphingolipid	regulates	pathway	0.50

Incoming (7)

Source	Relation	Type	Str
SPTLC1	causes	gene	0.50
CERS2	regulates	gene	0.50
SPTLC1	regulates	gene	0.50
SPTLC1	interacts_with	gene	0.50
GAIN	associated_with	gene	0.50
ABCA1	regulates	gene	0.50
SPTLC2	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SERINE PALMITOYLTRANSFERASE in their description or question text

No additional research found