gene

RPS10

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

4Outgoing

3Incoming

0Experiments

0Debates

Summary

RPS10 encodes a ribosomal protein of the 40S subunit involved in protein synthesis. Mutations cause Diamond-Blackfan anemia and are implicated in neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	RPS10
Function	is a highly conserved ribosomal protein that participates in multiple aspects of ribosome function.
Molecular Weight	18.9 kDa
Amino Acids	165 aa
Ensembl ID	ENSG00000124614
GeneCards	RPS10
Human Protein Atlas	RPS10
N-terminal region	Involved in rRNA binding
C-terminal domain	Mediates interactions with other ribosomal proteins
Surface residues	Form binding sites for translation factors
Inheritance	Autosomal dominant (most cases)
Mutation types	Missense, nonsense, frameshift
Associated Diseases	Alzheimer's disease, Parkinson's disease
Interactions	RPL35, RPL38, RPS16, RPS27, RPS28, TARDBP
KG Connections	7 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RPS10 Gene - Ribosomal Protein S10

gene · 2374 words

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Pathway Diagram

graph TD
    RPS10["RPS10"]
    Ms{"Ms"}
    RPS10 -->|"regulates"| Ms
    RPS16["RPS16"]
    RPS10 -->|"interacts with"| RPS16
    RPS27["RPS27"]
    RPS10 -->|"interacts with"| RPS27
    RPL38["RPL38"]
    RPS10 -->|"interacts with"| RPL38
    neurodegeneration["neurodegeneration"]
    RPS10 -->|"implicated in"| neurodegeneration
    RPS28["RPS28"]
    RPS28 -->|"interacts with"| RPS10
    RPL35["RPL35"]
    RPL35 -->|"interacts with"| RPS10
    TARDBP["TARDBP"]
    TARDBP -->|"interacts with"| RPS10
    style RPS10 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (4)

Target	Relation	Type	Str
Ms	regulates	disease	0.65
RPS16	interacts_with	gene	0.60
RPS27	interacts_with	gene	0.60
RPL38	interacts_with	gene	0.60

Incoming (3)

Source	Relation	Type	Str
RPS28	interacts_with	gene	0.60
RPL35	interacts_with	gene	0.60
TARDBP	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RPS10 in their description or question text

No additional research found