Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RNA-BINDING PROTEINS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | RNA-BINDING PROTEINS |
| Key Genes/Proteins | KAPB2 |
graph TD
RNA_BINDING_PROTEINS[RNA-BINDING PROTEINS]
RNA_BINDING_PROTEINS -->|regulates| RNA_Metabolism[RNA Metabolism]
RNA_BINDING_PROTEINS -->|regulates| Rna_Metabolism[Rna Metabolism]
RNA_BINDING_PROTEINS -->|regulates| Splicing[Splicing]
RNA_BINDING_PROTEINS -->|contributes to| Neurodegeneration[Neurodegeneration]
RNA_BINDING_PROTEINS -->|involved_in| Cytoplasmic_Mislocalization[Cytoplasmic Mislocalization]
RNA_BINDING_PROTEINS -->|involved_in| Stress_Granules[Stress Granules]
RNA_BINDING_PROTEINS -->|regulates| Cryptic_Splicing[Cryptic Splicing]
RNA_BINDING_PROTEINS -->|orchestrates| RNA_granules[RNA granules]
FUS[FUS] -->|interacts| RNA_BINDING_PROTEINS
KAPB2[KAPB2] -->|binds| RNA_BINDING_PROTEINS
tau_protein[tau protein] -->|interacts| RNA_BINDING_PROTEINS| Target | Relation | Type | Str |
|---|---|---|---|
| Neurodegeneration | contributes_to | process | 0.90 |
| Splicing | regulates | process | 0.90 |
| Rna Metabolism | regulates | process | 0.90 |
| RNA Metabolism | regulates | process | 0.90 |
| Cytoplasmic Mislocalization | involved_in | mechanism | 0.85 |
| Cryptic Splicing | regulates | process | 0.85 |
| Neurodegeneration | associated_with | process | 0.85 |
| Stress Granules | involved_in | process | 0.85 |
| Stress Granules | interacts_with | process | 0.85 |
| RNA granules | orchestrates | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| RNA foci | associated_with | structure | 0.90 |
| FUS | interacts_with | protein | 0.85 |
| KAPB2 | binds | protein | 0.80 |
| tau protein | interacts_with | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| RNA-binding proteins stabilize or gate the lncRNA-0021:mmu-m | 0.480 | molecular neurobiology | How does lncRNA-0021 achieve sequence-sp |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RNA-BINDING PROTEINS in their description or question text
No additional research found