Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAB5B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RAB5B |
| Chromosome | 12q13.2 |
| Function | encodes a member of the RAB family of small GTPases, which are key regulators of vesicle trafficking in eukaryotic cells. |
| Amino Acids | 216 aa |
| UniProt ID | P61020 |
| NCBI Gene ID | 5868 |
| Ensembl ID | ENSG00000167380 |
| GeneCards | RAB5B |
| Human Protein Atlas | RAB5B |
| Associated Diseases | neurodegeneration |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RAB5B["RAB5B"]
Carcinoma{"Carcinoma"}
RAB5B -->|"expressed in"| Carcinoma
Als{"Als"}
RAB5B -->|"expressed in"| Als
Cancer{"Cancer"}
RAB5B -->|"expressed in"| Cancer
Tumor{"Tumor"}
RAB5B -->|"expressed in"| Tumor
neurodegeneration["neurodegeneration"]
RAB5B -->|"implicated in"| neurodegeneration
MIRNAS["MIRNAS"]
MIRNAS -->|"expressed in"| RAB5B
BCL2L13["BCL2L13"]
BCL2L13 -->|"expressed in"| RAB5B
CANCER["CANCER"]
CANCER -->|"expressed in"| RAB5B
style RAB5B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RAB5B in their description or question text
No additional research found