concept

PARP14

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PARP14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

12Outgoing

5Incoming

0Experiments

0Debates

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💡 Concept Info

Name	PARP14
Key Genes/Proteins	ALOX5, ATM, GJA1, TGFBR1, ZEB1
Related Diseases	epilepsy, Epilepsy, Therapeutic target
Related Pathways	ferroptosis, mitochondrial function

Pathway Diagram

graph TD
    PARP14[PARP14]
    PARP14 -->|involved_in| Ferroptosis[Ferroptosis]
    PARP14 -->|implicated in| Epileptogenesis[Epileptogenesis]
    PARP14 -->|implicated in| Epilepsy[Epilepsy]
    PARP14 -->|target for| Therapeutic_target[Therapeutic target]
    PARP14 -->|participates in| ferroptosis[ferroptosis]
    PARP14 -->|activates| epilepsy[epilepsy]
    PARP14 -->|participates in| mitochondrial_function[mitochondrial function]
    PARP14 -->|expressed in| microglia[microglia]
    PARP14 -->|data_in| benchmark_ot_ad_answer_key_PAR[benchmark_ot_ad_answer_key:PARP14]
    GJA1[GJA1] -->|activates| PARP14
    benchmark_ot_ad_answer_key_PAR -->|data_in| PARP14

Outgoing (12)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:PARP14	data_in	dataset_row	0.00
Ferroptosis	involved_in	process	0.90
Epileptogenesis	implicated_in	process	0.85
Epilepsy	implicated_in	disease	0.85
Therapeutic target	therapeutic_target	phenotype	0.80
epilepsy	activates	disease	0.60
epilepsy	associated_with	disease	0.60
mitochondrial function	participates_in	pathway	0.60
microglia	expressed_in	cell_type	0.60
TGFBR1	associated_with	gene	0.60
ferroptosis	participates_in	pathway	0.60
ZEB1	associated_with	gene	0.60

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:PARP14	data_in	dataset_row	0.00
ALOX5	associated_with	gene	0.60
ATM	associated_with	gene	0.60
GJA1	associated_with	gene	0.60
GJA1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PARP14 in their description or question text

No additional research found