protein

NEPRILYSIN (NEP / CD10 / MME)

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEPRILYSIN (NEP / CD10 / MME): its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

1Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for Neprilysin (NEP / CD10 / MME)

View on Wiki →

No AI portrait yet

🔬 Protein Info

Gene Symbol	NEPRILYSIN
Aliases	NEP / CD10 / MME
Chromosome	3q25.2.
Protein Type	Protease
Function	is an important component in the neurobiology of neurodegenerative [diseases.
Primary Expression	Hippocampus
Molecular Weight	5 kDa
Amino Acids	750 aa
Pathways	Amyloid, Epigenetic, Apoptosis, Blood-Brain Barrier, Neuroinflammatory
GeneCards	NEPRILYSIN
Human Protein Atlas	NEPRILYSIN
Associated Diseases	Alzheimer, Alzheimer'S Disease, disease
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    A["Gene expression"] --> B["NEPRILYSIN NEP / CD10 / MME"]
    B --> C["Protein folding and
quality control"]
    B --> D["Cellular signaling"]
    C --> E["Proteostasis"]
    D --> F["Neurotoxicity"]
    E --> G["Disease outcome"]
    F --> G
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class B protein
    class G disease

Outgoing (1)

Target	Relation	Type	Str
SST	references	gene	0.40

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NEPRILYSIN (NEP / CD10 / MME) in their description or question text

No additional research found