protein

NFAT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NFAT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

4Outgoing

2Incoming

0Experiments

0Debates

Summary

Page for NFAT1 Protein

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🔬 Protein Info

Gene Symbol	NFAT1
Protein Type	Gene
Function	is an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight	120 kDa
Pathways	calcium signaling
GeneCards	NFAT1
Human Protein Atlas	NFAT1
Associated Diseases	neurodegeneration
Interactions	APP, BACE1, NFAT2, PP2B
KG Connections	6 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NFAT1 Gene

gene · 730 words

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NFAT1 Protein

protein · 871 words

→

Pathway Diagram

graph TD
    NFAT1(["NFAT1"])
    style NFAT1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    NFAT2(["NFAT2"])
    PP2B(["PP2B"])
    calcium_signaling(["calcium signaling"])
    T_cells(["T cells"])
    neurodegeneration["neurodegeneration"]

    NFAT1 -->|"activates"| NFAT2
    NFAT1 -->|"activates"| PP2B
    NFAT1 -->|"participates_in"| calcium_signaling
    NFAT1 -->|"expressed_in"| T_cells
    NFAT1 -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class NFAT2 protein
    class PP2B protein
    class calcium_signaling protein
    class T_cells protein
    class neurodegeneration disease

Outgoing (4)

Target	Relation	Type	Str
PP2B	activates	gene	0.55
T cells	expressed_in	cell_type	0.55
NFAT2	activates	gene	0.55
calcium signaling	participates_in	pathway	0.55

Incoming (2)

Source	Relation	Type	Str
APP	inhibits	gene	0.60
BACE1	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NFAT1 in their description or question text

No additional research found