concept

MIR125B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR125B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

20Connections

0Hypotheses

0Analyses

16Outgoing

4Incoming

0Experiments

0Debates

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💡 Concept Info

Name	MIR125B
Key Genes/Proteins	ALOX15, RELA, VDR
Related Diseases	Alzheimer's Disease, Alzheimer'S Disease
Related Pathways	neurotrophic signaling

Pathway Diagram

graph TD
    MIR125B[MIR125B]
    MIR125B -->|expressed in| Primary_Human_Neuronal_Glial_C[Primary Human Neuronal-Glial Cells]
    MIR125B -->|targets| ALOX15[ALOX15]
    MIR125B -.biomarker for.-> Alzheimer_s_Disease[Alzheimer's Disease]
    MIR125B -->|regulates| Neurotropic_Signaling[Neurotropic Signaling]
    MIR125B -->|inhibits| VDR[VDR]
    MIR125B -->|modulates| neurotrophic_signaling[neurotrophic signaling]
    MIR125B -->|inhibits| Neurotrophic_Support[Neurotrophic Support]
    RELA[RELA] -->|upregulates| MIR125B
    NFKB1[NFKB1] -->|activates| MIR125B
    benchmark_ot_ad_answer_key_MIR[benchmark_ot_ad_answer_key:MIR125B] -->|data_in| MIR125B

Outgoing (16)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MIR125B	data_in	dataset_row	0.00
Alzheimer'S Disease	associated_with	disease	0.95
Alzheimer's Disease	biomarker_for	disease	0.90
Alzheimer's Disease	implicated_in	disease	0.90
Primary Human Neuronal-Glial Cells	expressed_in	cell_type	0.90
ALOX15	targets	gene	0.90
neurotrophic signaling	modulates	pathway	0.85
Neurotropic Signaling	regulates	pathway	0.85
ALOX15	inhibits	gene	0.85
VDR	inhibits	gene	0.85
ALOX15	targets	gene	0.80
hippocampus CA1	expressed_in	brain_region	0.80
Neurotrophic Support	inhibits	process	0.80
Ca1 Region	expressed_in	brain_region	0.80
Inflammation	mediates	process	0.75
Reactive Oxygen Species Defense	associated_with	process	0.70

Incoming (4)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:MIR125B	data_in	dataset_row	0.00
RELA	upregulates	protein	0.90
NFKB1	activates	protein	0.85
RELA	regulates	protein	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIR125B in their description or question text

No additional research found