Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KLK7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | KLK7 |
| Key Genes/Proteins | AND, APOPTOSIS, App, Caspase, CASPASE14, INFLAMMATION |
| Related Diseases | Inflammation |
| Related Pathways | Apoptosis |
graph TD
KLK7["KLK7"]
KLK7 -->|"activates"| CASP14["CASP14"]
KLK7 -->|"cleaves"| PROCASPASE_14["PROCASPASE-14"]
KLK7 -->|"encodes"| KALLIKREIN7["KALLIKREIN7"]
KLK7 -->|"activates"| CASPASE14["CASPASE14"]
KLK7 -->|"activates"| Inflammation["Inflammation"]
KLK7 -->|"activates"| Apoptosis["Apoptosis"]
KLK7 -->|"activates"| APOPTOSIS["APOPTOSIS"]
KLK7 -->|"activates"| AND["AND"]
INFLAMMATION["INFLAMMATION"] -->|"activates"| KLK7
APOPTOSIS -->|"activates"| KLK7
AND -->|"activates"| KLK7| Target | Relation | Type | Str |
|---|---|---|---|
| KALLIKREIN7 | encodes | protein | 0.80 |
| CASPASE14 | activates | protein | 0.72 |
| Inflammation | activates | disease | 0.65 |
| Apoptosis | activates | pathway | 0.60 |
| Caspase | activates | protein | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| INFLAMMATION | activates | gene | 0.60 |
| App | activates | protein | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| INFLAMMATION | activates | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KLK7 in their description or question text
No additional research found