Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HELICOBACTER PYLORI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | HELICOBACTER PYLORI |
graph TD
HELICOBACTER_PYLORI[HELICOBACTER PYLORI]
HELICOBACTER_PYLORI -->|activates| NF__B[NF-ΚB]
HELICOBACTER_PYLORI -->|product_of| Outer_Membrane_Vesicles[Outer Membrane Vesicles]
HELICOBACTER_PYLORI -->|contributes to| ALZHEIMER_S_DISEASE[ALZHEIMER'S DISEASE]
HELICOBACTER_PYLORI -->|risk_factor_for| Alzheimer_s_Disease[Alzheimer's Disease]
HELICOBACTER_PYLORI -->|activates| MAPK[MAPK]
HELICOBACTER_PYLORI -->|causes| Dopaminergic_neuron_loss[Dopaminergic neuron loss]
HELICOBACTER_PYLORI -->|risk_factor_for| Parkinson_s_disease[Parkinson's disease]
HELICOBACTER_PYLORI -->|risk_factor_for| Glaucoma[Glaucoma]
HELICOBACTER_PYLORI -->|causes| __SYNUCLEIN[Α-SYNUCLEIN]| Target | Relation | Type | Str |
|---|---|---|---|
| NF-ΚB | activates | protein | 0.95 |
| Outer Membrane Vesicles | associated_with | compound | 0.95 |
| Outer Membrane Vesicles | product_of | compound | 0.90 |
| ALZHEIMER'S DISEASE | contributes_to | disease | 0.90 |
| ALZHEIMER'S DISEASE | risk_factor_for | disease | 0.85 |
| Neuroinflammation | associated_with | process | 0.85 |
| Alzheimer's Disease | risk_factor_for | disease | 0.85 |
| MAPK | activates | pathway | 0.85 |
| Dopaminergic neuron loss | causes | phenotype | 0.80 |
| Parkinson's disease | risk_factor_for | disease | 0.80 |
| DNA Damage | associated_with | process | 0.80 |
| Chronic Inflammation | associated_with | process | 0.80 |
| Cell Apoptosis | associated_with | process | 0.80 |
| Glaucoma | risk_factor_for | disease | 0.75 |
| Α-SYNUCLEIN | causes | protein | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HELICOBACTER PYLORI in their description or question text
No additional research found