Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GABA-A RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GABA-A RECEPTOR |
graph TD
GABA_A_RECEPTOR[GABA-A RECEPTOR]
GABA_A_RECEPTOR -->|modulates| Seizures[Seizures]
GABA_A_RECEPTOR -->|expressed in| Optic_nerve[Optic nerve]
GABA_A_RECEPTOR -->|expressed in| cortex[cortex]
GABA_A_RECEPTOR -->|expressed in| microglia[microglia]
GABA_A_RECEPTOR -->|expressed in| neurons[neurons]
GABRA1[GABRA1] -->|involved_in| GABA_A_RECEPTOR
GABRG2[GABRG2] -->|involved_in| GABA_A_RECEPTOR
caffeine[caffeine] -->|modulates| GABA_A_RECEPTOR
epilepsy[epilepsy] -->|involves| GABA_A_RECEPTOR
GABA[GABA] -->|inhibits| GABA_A_RECEPTOR
neurodegeneration[neurodegeneration] -->|involves| GABA_A_RECEPTOR
aging[aging] -->|involves| GABA_A_RECEPTOR| Source | Relation | Type | Str |
|---|---|---|---|
| GABRA1 | involved_in | gene | 0.95 |
| GABRG2 | involved_in | gene | 0.95 |
| caffeine | modulates | drug | 0.75 |
| GABA | inhibits | gene | 0.70 |
| epilepsy | involves | disease | 0.70 |
| neurodegeneration | involves | disease | 0.60 |
| GABA | promotes | gene | 0.60 |
| GABA | causes | gene | 0.60 |
| aging | involves | disease | 0.60 |
| GABA | regulates | gene | 0.60 |
| GABA | modulates | gene | 0.60 |
| GABA | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GABA-A RECEPTOR in their description or question text
No additional research found