gene

FBXO45

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FBXO45: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

5Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for FBXO45 - F-Box Protein 45

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🧬 Gene Info

Gene Symbol	FBXO45
Full Name	F-Box Protein 45
Aliases	Page for FBXO45
Chromosome	3q29
Function	FBXO45 contains an F-box domain that recruits the protein to the SCF ubiquitin ligase complex.
Primary Expression	Brain, Spinal cord, Muscle
UniProt ID	Q9C0B1
NCBI Gene ID	200185
Ensembl ID	ENSG00000157542
GeneCards	FBXO45
Human Protein Atlas	FBXO45
Interactions	EPHB2, MYC, UBIQUITIN
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FBXO45 — AlphaFold Q9C0B1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

FBXO45 - F-Box Protein 45

gene · 641 words

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Pathway Diagram

graph TD
    FBXO45["FBXO45"]
    Als{"Als"}
    FBXO45 -->|"interacts with"| Als
    Ms{"Ms"}
    FBXO45 -->|"interacts with"| Ms
    MYC["MYC"]
    FBXO45 -->|"interacts with"| MYC
    EPHB2["EPHB2"]
    FBXO45 -->|"interacts with"| EPHB2
    UBIQUITIN["UBIQUITIN"]
    FBXO45 -->|"interacts with"| UBIQUITIN
    neurodegeneration["neurodegeneration"]
    FBXO45 -->|"implicated in"| neurodegeneration
    style FBXO45 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Als	interacts_with	disease	0.65
Ms	interacts_with	disease	0.65
MYC	interacts_with	gene	0.60
EPHB2	interacts_with	gene	0.60
UBIQUITIN	interacts_with	gene	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FBXO45 in their description or question text

No additional research found