Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ET1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| YAP | activates | protein | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PLGF | inhibits | protein | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Neuronal TET1 Upregulation Reactivates Immediate-Early Genes | 0.640 | neurodegeneration | epigenetic reprogramming aging neurons |
| Targeted DNA Demethylation at the Klotho Locus via dCas9-TET | 0.510 | neurodegeneration | epigenetic reprogramming aging neurons |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ET1 in their description or question text
No additional research found