concept

DERMATOMYOSITIS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DERMATOMYOSITIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

0Outgoing

14Incoming

0Experiments

0Debates

No summary available yet.

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💡 Concept Info

Name	DERMATOMYOSITIS
Key Genes/Proteins	HSPA1A

Pathway Diagram

graph TD
    DERMATOMYOSITIS["DERMATOMYOSITIS"]
    CXCL10["CXCL10"] -->|"upregulates"| DERMATOMYOSITIS
    PI3K_AKT_Signaling["PI3K/AKT Signaling"] -->|"involved_in"| DERMATOMYOSITIS
    ERK_Signaling["ERK Signaling"] -->|"involved_in"| DERMATOMYOSITIS
    p38_MAPK_Signaling["p38 MAPK Signaling"] -->|"involved_in"| DERMATOMYOSITIS
    PI3K_AKT["PI3K/AKT"] -->|"upregulates"| DERMATOMYOSITIS
    ERK["ERK"] -->|"upregulates"| DERMATOMYOSITIS
    p38_MAPK["p38 MAPK"] -->|"upregulates"| DERMATOMYOSITIS

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (14)

Source	Relation	Type	Str
CXCL10	upregulates	gene	0.95
CXCL10	biomarker_for	gene	0.90
PI3K/AKT Signaling	involved_in	pathway	0.90
ERK Signaling	involved_in	pathway	0.90
p38 MAPK Signaling	involved_in	pathway	0.90
PI3K/AKT	upregulates	pathway	0.88
ERK	upregulates	pathway	0.88
p38 MAPK	upregulates	pathway	0.88
Neutrophil Degranulation	contributes_to	process	0.85
Glycolysis	upregulates	pathway	0.85
Granzyme B Signaling	associated_with	pathway	0.75
Sirtuin Signaling	associated_with	pathway	0.75
Aryl Hydrocarbon Receptor Signaling	associated_with	pathway	0.75
HSPA1A	associated_with	protein	0.72

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DERMATOMYOSITIS in their description or question text

No additional research found