gene

DLX2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DLX2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

5Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for DLX2 Gene

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🧬 Gene Info

Gene Symbol	DLX2
Full Name	Distal-Less Homeobox 2
Chromosome	2q31.1
Protein Type	Transcription Factor
Function	essential for forebrain development, GABAergic neuron differentiation, and craniofacial morphogenesis
Primary Expression	developing forebrain
Molecular Weight	32 kDa
Amino Acids	175 aa
UniProt ID	Q9UBX3
NCBI Gene ID	1749
GeneCards	DLX2
Human Protein Atlas	DLX2
Associated Diseases	neurodegeneration
KG Connections	8 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DLX2 — AlphaFold Q9UBX3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

DLX2 Gene

gene · 811 words

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DLX2 Protein

protein · 1057 words

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Pathway Diagram

graph TD
    DLX2["DLX2"]
    Schizophrenia{"Schizophrenia"}
    DLX2 -->|"activates"| Schizophrenia
    Aging{"Aging"}
    DLX2 -->|"activates"| Aging
    Depression{"Depression"}
    DLX2 -->|"activates"| Depression
    Bipolar{"Bipolar"}
    DLX2 -->|"activates"| Bipolar
    Ms{"Ms"}
    DLX2 -->|"activates"| Ms
    neurodegeneration["neurodegeneration"]
    DLX2 -->|"implicated in"| neurodegeneration
    NGN2["NGN2"]
    NGN2 -->|"associated with"| DLX2
    DISC1["DISC1"]
    DISC1 -->|"associated with"| DLX2
    ASCL1["ASCL1"]
    ASCL1 -->|"associated with"| DLX2
    style DLX2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

Target	Relation	Type	Str
Schizophrenia	activates	disease	0.65
Aging	activates	disease	0.65
Depression	activates	disease	0.65
Bipolar	activates	disease	0.65
Ms	activates	disease	0.65

Incoming (3)

Source	Relation	Type	Str
NGN2	associated_with	gene	0.60
DISC1	associated_with	gene	0.60
ASCL1	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DLX2 in their description or question text

No additional research found